/* Leleon Life Science design system. Register: clinical authority.
   Palette: deep plum + brand magenta (from the lion logo) on a warm field.
   Type: Libre Caslon Text (headings) / Source Sans 3 (body) / IBM Plex Mono (data). */

/* ---------- fonts (self-hosted) ---------- */
@font-face{font-family:"Libre Caslon Text";font-style:normal;font-weight:400;font-display:swap;src:url("../fonts/libre-caslon-text-400.woff2") format("woff2")}
@font-face{font-family:"Libre Caslon Text";font-style:normal;font-weight:700;font-display:swap;src:url("../fonts/libre-caslon-text-700.woff2") format("woff2")}
@font-face{font-family:"Source Sans 3";font-style:normal;font-weight:400;font-display:swap;src:url("../fonts/source-sans-3-400.woff2") format("woff2")}
@font-face{font-family:"Source Sans 3";font-style:normal;font-weight:600;font-display:swap;src:url("../fonts/source-sans-3-600.woff2") format("woff2")}
@font-face{font-family:"Source Sans 3";font-style:normal;font-weight:700;font-display:swap;src:url("../fonts/source-sans-3-700.woff2") format("woff2")}
@font-face{font-family:"IBM Plex Mono";font-style:normal;font-weight:400;font-display:swap;src:url("../fonts/ibm-plex-mono-400.woff2") format("woff2")}
@font-face{font-family:"IBM Plex Mono";font-style:normal;font-weight:500;font-display:swap;src:url("../fonts/ibm-plex-mono-500.woff2") format("woff2")}

/* ---------- tokens ---------- */
:root{
  --field:#FBF7F5;          /* warm off-white page ground */
  --surface:#FFFFFF;
  --ink:#27141F;            /* near-black plum ink */
  --muted:#5F4A56;          /* plum-grey secondary text (4.5+:1 on field) */
  --plum:#6A1A52;           /* primary brand */
  --plum-hover:#571544;
  --plum-deep:#340D29;      /* dark section ground */
  --magenta:#A81C87;        /* accent for text on light (>=4.5:1) */
  --gold:#755A18;           /* restrained secondary accent on light */
  --gold-od:#E9C979;        /* gold for dark grounds */
  --line:#E9DCE4;
  --chip:#F4E7F0;
  /* on-dark tokens */
  --od-text:#F8EFF5;
  --od-muted:#D8BDCD;
  --od-accent:#F2A9DC;
  --od-gold:#E3B85C;
  --od-line:#5C3A50;
  --lb-accent:#F2A9DC;
  --lb-muted:#D8BDCD;
  --font-h:"Libre Caslon Text",Georgia,serif;
  --font-b:"Source Sans 3",-apple-system,"Segoe UI",Arial,sans-serif;
  --font-m:"IBM Plex Mono",ui-monospace,Menlo,monospace;
  --wrap:1120px;
  --r:10px;
}

/* ---------- reset-ish ---------- */
*,*::before,*::after{box-sizing:border-box}
html{scroll-behavior:smooth}
@media (prefers-reduced-motion:reduce){
  html{scroll-behavior:auto}
  *,*::before,*::after{animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important}
}
body{margin:0;background:var(--field);color:var(--ink);font:400 1.0625rem/1.65 var(--font-b);-webkit-font-smoothing:antialiased}
img{max-width:100%;height:auto;display:block}
h1,h2,h3,h4{font-family:var(--font-h);line-height:1.18;color:var(--ink);margin:0 0 .5em;text-wrap:balance;font-weight:700}
h1{font-size:clamp(2rem,4.5vw,3.1rem)}
h2{font-size:clamp(1.5rem,3vw,2.15rem)}
h3{font-size:1.2rem}
p{margin:0 0 1em}
a{color:var(--plum)}
a:focus-visible,button:focus-visible,summary:focus-visible,input:focus-visible{outline:3px solid var(--magenta);outline-offset:2px;border-radius:2px}
.wrap{max-width:var(--wrap);margin:0 auto;padding:0 20px}
.sr-only{position:absolute!important;width:1px;height:1px;margin:-1px;padding:0;border:0;clip:rect(0,0,0,0);overflow:hidden;white-space:nowrap;opacity:0}
.skip{position:absolute;left:-999px;top:0;background:var(--plum);color:#fff;padding:10px 18px;z-index:200;border-radius:0 0 8px 0}
.skip:focus{left:0}

/* ---------- header ---------- */
.site-head{background:var(--surface);border-bottom:1px solid var(--line);position:sticky;top:0;z-index:100}
.head-in{display:flex;align-items:center;gap:18px;min-height:72px}
.brand{display:inline-flex;align-items:center;background:#fff;border:1px solid var(--line);border-radius:10px;padding:6px 12px;text-decoration:none}
.brand img{display:block;height:36px;width:auto;max-width:min(210px,32vw);object-fit:contain;object-position:left center}
.site-nav{margin-left:auto;min-width:0}
.nav-toggle{display:none}
.nav-btn{display:none;margin-left:auto;background:var(--plum);color:#fff;border:0;border-radius:8px;padding:14px 12px;font:600 1rem var(--font-b);cursor:pointer}
.nav-ico{position:relative;display:block;width:22px;height:2px;background:currentColor;transition:background .12s}
.nav-ico::before,.nav-ico::after{content:"";position:absolute;left:0;width:22px;height:2px;background:currentColor;transition:transform .18s,top .18s}
.nav-ico::before{top:-7px}
.nav-ico::after{top:7px}
.nav-toggle:checked~.nav-label .nav-ico,.nav-btn[aria-expanded="true"] .nav-ico{background:transparent}
.nav-toggle:checked~.nav-label .nav-ico::before,.nav-btn[aria-expanded="true"] .nav-ico::before{top:0;transform:rotate(45deg)}
.nav-toggle:checked~.nav-label .nav-ico::after,.nav-btn[aria-expanded="true"] .nav-ico::after{top:0;transform:rotate(-45deg)}
.site-nav ul{list-style:none;display:flex;gap:0;margin:0;padding:0;align-items:center;flex-wrap:nowrap}
.site-nav a{display:block;padding:10px 9px;text-decoration:none;color:var(--ink);font-weight:600;font-size:.93rem;border-radius:8px;white-space:nowrap}
.site-nav a:hover{background:var(--chip);color:var(--plum)}
.site-nav a[aria-current="page"]{color:var(--plum);box-shadow:inset 0 -3px 0 var(--magenta)}
.site-nav .nav-cta a{background:var(--plum);color:#fff;padding:10px 14px;border-radius:999px}
.site-nav .nav-cta a:hover{background:var(--plum-hover);color:#fff}
@media (min-width:921px) and (max-width:1180px){
  .head-in{gap:10px}
  .brand img{max-width:min(150px,24vw)}
  .site-nav a{font-size:.84rem;padding:10px 6px}
  .site-nav .nav-cta a{padding:10px 11px;font-size:.84rem}
}
@media (max-width:920px){
  .nav-btn{display:inline-block}
  .site-nav{position:absolute;left:0;right:0;top:100%;background:var(--surface);border-bottom:1px solid var(--line);display:none;margin:0;box-shadow:0 18px 30px rgba(39,20,31,.12)}
  .nav-toggle:checked ~ .site-nav,.site-nav.open{display:block}
  .site-nav ul{flex-direction:column;align-items:stretch;padding:10px 20px 18px}
  .site-nav .nav-cta a{text-align:center}
  .brand{background:transparent;border:0;padding:0}
  .brand img{height:48px;max-width:min(380px,64vw)}
  /* no-JS fallback: label shows when JS has not replaced it */
  .nav-label{display:inline-flex;align-items:center;margin-left:auto;background:var(--plum);color:#fff;border-radius:8px;padding:14px 12px;font-weight:600;cursor:pointer}
}
@media (min-width:921px){.nav-label{display:none}}

/* ---------- hero ---------- */
.hero{background:linear-gradient(160deg,var(--plum-deep) 0%,#4A1239 55%,var(--plum) 100%);color:var(--od-text);position:relative;overflow:hidden}
.hero .wrap{position:relative;padding-top:clamp(52px,8vw,84px);padding-bottom:clamp(52px,8vw,84px)}
.hero h1{color:#fff;max-width:17ch}
.hero p{color:var(--od-text);max-width:58ch;font-size:1.15rem}
.hero .lionmark{position:absolute;right:4vw;bottom:-8%;width:clamp(420px,38vw,720px);opacity:.45;mix-blend-mode:multiply;pointer-events:none}
.page-hero{background:linear-gradient(160deg,var(--plum-deep),#4A1239);color:var(--od-text);position:relative;overflow:hidden}
.page-hero .wrap{position:relative;padding-top:clamp(36px,5.5vw,56px);padding-bottom:clamp(36px,5.5vw,56px)}
.page-hero h1{color:#fff}
.page-hero p{color:var(--od-text);max-width:62ch}
.hero .eyebrow,.page-hero .eyebrow,.cta-band .eyebrow,.section--plum .eyebrow,.notfound .eyebrow{color:var(--od-accent)}
.crumbs{font-size:.9rem;margin:0 0 14px;color:var(--od-muted)}
.crumbs a{color:var(--od-text)}
.crumbs span[aria-current]{color:var(--od-muted)}

/* ---------- shared bits ---------- */
.eyebrow{font:500 .8rem var(--font-m);letter-spacing:.14em;text-transform:uppercase;color:var(--magenta);display:block;margin:0 0 10px}
.section{padding:clamp(44px,7vw,72px) 0}
.section--alt{background:var(--surface);border-top:1px solid var(--line);border-bottom:1px solid var(--line)}
.section--plum{background:var(--plum-deep);color:var(--od-text)}
.section--plum h2,.section--plum h3{color:#fff}
.section--plum p:not(.eyebrow){color:var(--od-text)}
.section--plum a:not(.btn){color:var(--od-accent)}
.section-head{max-width:70ch;margin-bottom:36px}
.section-head p:not(.eyebrow){color:var(--muted);font-size:1.08rem}
.btn{display:inline-block;font:600 1.02rem var(--font-b);text-decoration:none;border-radius:999px;padding:13px 26px;border:2px solid transparent;cursor:pointer}
.btn-primary{background:var(--plum);color:#fff}
.btn-primary:hover{background:var(--plum-hover)}
.btn-secondary{background:transparent;color:var(--plum);border-color:var(--plum)}
.btn-secondary:hover{background:var(--chip)}
.hero .btn-primary,.page-hero .btn-primary,.cta-band .btn-primary,.section--plum .btn-primary{background:#fff;color:var(--plum)}
.hero .btn-primary:hover,.page-hero .btn-primary:hover,.cta-band .btn-primary:hover,.section--plum .btn-primary:hover{background:var(--od-text)}
.hero .btn-secondary,.page-hero .btn-secondary,.cta-band .btn-secondary,.section--plum .btn-secondary,.notfound .btn-secondary{color:#fff;border-color:var(--od-accent)}
.hero .btn-secondary:hover,.page-hero .btn-secondary:hover,.cta-band .btn-secondary:hover,.section--plum .btn-secondary:hover,.notfound .btn-secondary:hover{background:rgba(242,169,220,.14)}
.notfound .btn-primary{background:#fff;color:var(--plum)}
.btn-row{display:flex;gap:14px;flex-wrap:wrap;margin-top:26px}
.mono{font-family:var(--font-m);font-size:.92em}

/* trust strip */
.trust{display:grid;grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:1px;background:var(--line);border:1px solid var(--line);border-radius:var(--r);overflow:hidden;margin-top:-42px;position:relative;z-index:2}
.trust > div{background:var(--surface);padding:20px 22px}
.trust b{display:block;font-family:var(--font-h);font-size:1.35rem;color:var(--plum)}
.trust span{color:var(--muted);font-size:.95rem}

/* cards */
.cards{display:grid;grid-template-columns:repeat(auto-fit,minmax(250px,1fr));gap:22px}
.card{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);padding:26px}
.card h3{margin-top:10px}
.card p{color:var(--muted);font-size:.99rem;margin:0}
.card .ico{width:44px;height:44px;color:var(--plum)}
.card a{font-weight:600}

/* product cards */
.prods{display:grid;grid-template-columns:repeat(auto-fill,minmax(255px,1fr));gap:22px}
.prod{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);overflow:hidden;display:flex;flex-direction:column}
a.prod-link{color:inherit;text-decoration:none;transition:border-color .15s,box-shadow .15s}
a.prod-link:hover{border-color:var(--plum);box-shadow:0 6px 20px rgba(106,26,82,.08)}
a.prod-link:hover h3{color:var(--plum-hover)}
.prod .shot{aspect-ratio:16/9;background:var(--chip);display:flex;flex-direction:column;align-items:stretch;justify-content:flex-start;overflow:hidden;position:relative}
.prod .shot img{width:100%;flex:1;min-height:0;object-fit:contain;background:#fff}
.prod .shot .ph-badge{margin:0;padding:8px 10px;text-align:center;flex-shrink:0}
.prod .shot .lionph{width:56px;opacity:.28;border-radius:14px;margin:auto}
.prod .body{padding:20px 22px 22px;display:flex;flex-direction:column;gap:8px;flex:1}
.prod h3{margin:0;font-size:1.15rem;color:var(--plum)}
.prod .mol{font:400 .85rem var(--font-m);color:var(--muted);margin:0}
.prod .tag{align-self:flex-start;background:var(--chip);color:var(--plum);font:600 .78rem var(--font-b);letter-spacing:.04em;border-radius:999px;padding:3px 12px;text-transform:uppercase}

/* therapy jump nav + audience chips */
.ta-jump{font:600 .95rem var(--font-b);line-height:1.8;color:var(--muted)}
.ta-jump a{color:var(--plum);text-decoration:none;padding:2px 0}
.ta-jump a:hover{text-decoration:underline;color:var(--plum-hover)}
.page-hero .ta-jump{color:var(--od-muted)}
.page-hero .ta-jump a{color:var(--od-text)}
.page-hero .ta-jump a:hover{color:var(--od-accent)}
.audience-chips{display:flex;flex-wrap:wrap;gap:10px;margin-top:22px}
.chip-link{display:inline-block;background:rgba(255,255,255,.12);border:1px solid var(--od-line);color:var(--od-text);font:600 .88rem var(--font-b);text-decoration:none;border-radius:999px;padding:8px 16px}
.chip-link:hover{background:rgba(242,169,220,.16);border-color:var(--od-accent);color:#fff}
.section .audience-chips{margin-top:0;margin-bottom:8px}
.section .chip-link{background:var(--chip);border-color:var(--line);color:var(--plum)}
.section .chip-link:hover{background:var(--surface);border-color:var(--plum)}

/* A–Z brand list (patients) */
.brand-az{list-style:none;margin:0;padding:0;border:1px solid var(--line);border-radius:var(--r);background:var(--surface);overflow:hidden}
.brand-az li{display:flex;flex-wrap:wrap;align-items:baseline;gap:8px 16px;padding:14px 20px;border-top:1px solid var(--line)}
.brand-az li:first-child{border-top:0}
.brand-az a{text-decoration:none;color:var(--plum)}
.brand-az a:hover{text-decoration:underline}
.brand-az .mono{font-size:.88rem;color:var(--muted);flex:1;min-width:180px}

/* product page: pack first on small screens */
.split--product{align-items:start}
.split--product .split-media img,.split--product .ph-block--media{width:100%}
@media (max-width:820px){
  .split--product{grid-template-columns:1fr}
  .split--product .split-media{order:-1}
}

/* collapsible monograph */
.mono-stack{max-width:820px}
.mono-detail{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);margin-bottom:12px}
.mono-detail summary{cursor:pointer;padding:18px 22px;font-weight:700;font-family:var(--font-b);font-size:1.05rem;list-style:none;position:relative;padding-right:48px;color:var(--ink)}
.mono-detail summary::-webkit-details-marker{display:none}
.mono-detail summary::after{content:"+";position:absolute;right:20px;top:50%;transform:translateY(-50%);font:400 1.5rem var(--font-m);color:var(--magenta)}
.mono-detail[open] summary::after{content:"\2212"}
.mono-detail .mono-body{padding:0 22px 20px;color:var(--muted);line-height:1.72;font-size:1.02rem}
.mono-detail .mono-body p{margin:0 0 14px}
.mono-detail .mono-body h3{font-family:var(--font-b);font-size:1.05rem;font-weight:700;margin:18px 0 10px;color:var(--ink)}
.mono-detail .mono-body ul,.mono-detail .mono-body ol{margin:0 0 14px 1.25em;padding:0}
.mono-detail .mono-body li{margin-bottom:8px}

/* split section */
.split{display:grid;grid-template-columns:1.05fr 1fr;gap:48px;align-items:center}
.split img{border-radius:var(--r);border:1px solid var(--line)}
@media (max-width:820px){.split{grid-template-columns:1fr}}

/* fact table (product pages) */
.facts{width:100%;border-collapse:collapse;background:var(--surface);border:1px solid var(--line);border-radius:var(--r);overflow:hidden;font-size:1rem}
.facts th,.facts td{text-align:left;padding:13px 18px;border-top:1px solid var(--line);vertical-align:top}
.facts tr:first-child th,.facts tr:first-child td{border-top:0}
.facts th{width:200px;color:var(--muted);font:600 .86rem var(--font-b);letter-spacing:.03em;text-transform:uppercase}
.facts td{font-family:var(--font-b)}
.facts td .mono{color:var(--plum)}
.table-scroll{overflow-x:auto}
.todo{display:inline-block;border:1.5px dashed var(--gold);color:var(--gold);border-radius:6px;padding:1px 10px;font:600 .78rem var(--font-b);letter-spacing:.06em;text-transform:uppercase}
.hero .todo,.page-hero .todo,.cta-band .todo,.section--plum .todo,.notfound .todo{color:var(--gold-od);border-color:var(--gold-od)}
.preview-banner{background:#fff8e6;border-bottom:2px dashed var(--gold);padding:12px 0;font-size:.95rem;text-align:center;color:var(--ink)}
.preview-banner strong{color:var(--plum)}
.preview-page-note{margin-top:14px;font-size:.98rem;color:var(--muted)}
.pack-preview-note{margin:8px 0 0;font-size:.92rem;color:var(--muted);line-height:1.55;text-align:center}
.pack-figure{margin:0}
.pack-figure img{display:block;width:100%;height:auto}
.pack-figure .ph-badge{text-align:center;margin-top:10px}
.split--product .pack-preview-note{max-width:36em;margin-left:auto;margin-right:auto}
.split--product .split-media .safety-callout{margin-top:20px}
.ph-block{border:2px dashed var(--gold);border-radius:var(--r);padding:20px 22px;background:#fffdf8;margin:16px 0}
.ph-block--media{min-height:200px;display:flex;flex-direction:column;align-items:center;justify-content:center;text-align:center}
.ph-badge{margin:0 0 10px}
.ph-block h3{margin:0 0 8px;color:var(--ink);font-size:1.08rem;font-family:var(--font-h)}
.ph-note{margin:0;color:var(--muted);font-size:.94rem;line-height:1.55}
.ph-note-inline{display:block;margin-top:6px;font-size:.9rem;color:var(--muted);line-height:1.5}
.card .ph-block{margin-top:0}
.card .ph-block--media{margin-bottom:16px}
.hcp-note,.consult-note{background:var(--chip);border-left:4px solid var(--plum);border-radius:6px;padding:14px 18px;color:var(--plum);font-weight:600;font-size:.98rem;margin:22px 0}
.safety-callout{background:var(--surface);border:3px solid var(--plum);border-radius:var(--r);padding:36px 28px;text-align:center;max-width:820px;margin:0 auto}
.safety-line{margin:0 0 18px;font-family:var(--font-h);font-size:clamp(1.35rem,3.2vw,1.75rem);font-weight:700;color:var(--plum);line-height:1.3}
.safety-line:last-child{margin-bottom:0}
.section.safety-footer{padding-top:0}
.mono-section{max-width:820px}
.mono-section h2{font-family:var(--font-h);font-size:1.45rem;margin:0 0 16px;color:var(--ink)}
.mono-body{color:var(--muted);line-height:1.72;font-size:1.02rem}
.mono-body p{margin:0 0 14px}
.mono-body h3{font-family:var(--font-b);font-size:1.05rem;font-weight:700;margin:18px 0 10px;color:var(--ink)}
.mono-body ul,.mono-body ol{margin:0 0 14px 1.25em;padding:0}
.mono-body li{margin-bottom:8px}
.rx-flag{font:500 .8rem var(--font-m);color:var(--muted)}

/* steps / why */
.steps{display:grid;grid-template-columns:repeat(auto-fit,minmax(230px,1fr));gap:22px;counter-reset:step}
.step{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);padding:24px}
.step h3{color:var(--ink)}
.step .num{font:500 1rem var(--font-m);color:var(--magenta)}
.section--plum .step h3{color:var(--ink)}
.section--plum .step p{color:var(--muted)}
.section--plum .step .num{color:var(--magenta)}

/* FAQ */
.faq details{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);margin-bottom:12px}
.faq summary{cursor:pointer;padding:18px 22px;font-weight:700;font-family:var(--font-b);font-size:1.05rem;list-style:none;position:relative;padding-right:48px}
.faq summary::-webkit-details-marker{display:none}
.faq summary::after{content:"+";position:absolute;right:20px;top:50%;transform:translateY(-50%);font:400 1.5rem var(--font-m);color:var(--magenta)}
.faq details[open] summary::after{content:"\2212"}
.faq .a{padding:0 22px 20px;color:var(--muted)}

/* contact starters */
.starters{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:22px}
.starter{background:var(--surface);border:1px solid var(--line);border-radius:var(--r);padding:24px;display:flex;flex-direction:column;gap:10px}
.starter h3{margin:0}
.starter p{color:var(--muted);margin:0;flex:1}
.starter .btn{align-self:flex-start}

/* CTA band */
.cta-band{background:linear-gradient(135deg,var(--plum) 0%,var(--plum-deep) 90%);color:var(--od-text);border-radius:var(--r)}
.cta-band .in{padding:clamp(28px,5vw,52px);display:flex;flex-wrap:wrap;align-items:center;gap:26px;justify-content:space-between}
.cta-band h2{color:#fff;margin:0;max-width:24ch}
.cta-band p:not(.eyebrow){color:var(--od-text);margin:6px 0 0;max-width:52ch}

/* footer */
.site-foot{background:var(--plum-deep);color:var(--od-text);margin-top:72px}
.foot-in{display:grid;grid-template-columns:1.2fr 1fr 1fr;gap:40px;padding:56px 0 36px}
@media (max-width:1020px) and (min-width:821px){.foot-in{grid-template-columns:1fr 1fr;gap:32px}.footer-brand{grid-column:1/-1}}
@media (max-width:820px){.foot-in{grid-template-columns:1fr;gap:28px;padding:40px 0 24px}.site-foot{margin-top:56px;padding: 0 20px;}.footer-brand .brand img{height:60px}}
.footer-brand .brand{background:#fff}
.footer-brand .brand img{height:74px}
.site-foot h3{color:#fff;font-size:1rem;font-family:var(--font-b);letter-spacing:.08em;text-transform:uppercase}
.site-foot ul{list-style:none;margin:0;padding:0}
.site-foot li{margin:8px 0}
.site-foot a{color:var(--od-text)}
.site-foot a:hover{color:var(--od-accent)}
.site-foot .muted{color:var(--od-muted);font-size:.95rem}
.foot-legal{border-top:1px solid var(--od-line);padding:22px 0 30px;font-size:.9rem;color:var(--od-muted)}
.foot-legal p{margin:0 0 8px}
.standards{font-size:.84rem;color:var(--od-muted)}

/* notfound */
.notfound{background:var(--plum-deep);color:var(--od-text);min-height:60vh;display:flex;align-items:center}
.notfound h1{color:#fff}
.notfound p{color:var(--od-text)}

/* inline icons */
.ico{display:inline-block;stroke:currentColor;fill:none;stroke-width:1.6;stroke-linecap:round;stroke-linejoin:round}

/* utilities */
.grid-2{display:grid;grid-template-columns:1fr 1fr;gap:40px}
@media (max-width:820px){.grid-2{grid-template-columns:1fr}}
.note-sm{font-size:.9rem;color:var(--muted)}
.section--plum .note-sm{color:var(--od-muted)}